Additional analyses using alternate definitions for CKD and cross-sectional study did not change the results.
Although we defined and graded IAH and ACS according to the definitions developed by the WSACS [ 14], studies using alternate definitions or grading schemes for these conditions were also included.
7 Still, the "Salient Principle" has not been supported by other studies that used alternate definitions for severe diarrhea among children under five.
Results were similar using the alternate definitions of catastrophic medical spending (difference ranging from 1.6% [medical spending ≥40% of total spending; P = 0.016] to 5.2% [medical spending ≥10% of total spending; P = 0.013]) (Supplementary Table 4).
Additionally, microalbuminuria was associated with accelerated MOD incidence in both cohorts, although to a greater degree in the 1960s cohort (k = 13.2, P < 0.0001 vs. 1970s, k = 3.0, P = 0.008), and these results did not differ when using an alternate definition of microalbuminuria that included the use of ACE inhibitors.
Other sensitivity analyses indicated that all results were qualitatively robust (similar magnitude, direction, and significance) to using an alternate definition of airflow limitation and restricting to individuals who had not moved in the previous 10 years (results not shown).
24 29 When we used an alternate definition of osteoarthritis, however, we found much the same results (web appendix 2).
In an additional sensitivity analysis, we used an alternate definition of treatment failure (death, hospitalization [for primary-care patients], rehospitalization [for hospitalized patients], and ICU admission [for non-ICU patients at randomization]).
We observed significant associations of NK cytotoxicity with living near arterials when using alternate cut points of either 100 or 200 m for our definition of proximity to traffic, and the magnitudes of the associations were similar to our main analysis, indicating that this result was not excessively sensitive to our a priori cut point of 150 m.
The Census Bureau does take into account housing costs when formulating alternate definitions of the poverty line, but does not break down those estimates by state, Ms. Reed said.
