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Hazard ratios were estimated by using a weighted cohort approach.
Finally, data were also analyzed using a weighted cohort approach [ 39] to allow for the retrospective study design and, in particular, the nonrandom sampling of affected and unaffected mutation carriers.
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To correct for this potential bias we used a weighted cohort approach to analyse the effect of parity [ 16].
To overcome bias when subjects are selected on the basis of phenotype, we used a weighted cohort approach (Antoniou et al, 2005), which has been successfully utilised for studies of modifiers of cancer risk of rare genetic mutations (e.g., Andrieu et al, 2006; Antoniou et al, 2008; Win et al, 2011).
To obtain an NICHD cohort similar to our 23 25 week cohort (mean birthweight 664 grams) we combined the 550 and 750 gram NICHD cohorts using a weighted average and pooled standard deviations.
Hazard ratios for case-cohort studies are typically estimated using a weighted version of the Cox proportional hazards model [ 1].
SNP effects were estimated using a weighted Z-score of the beta values calculated using a linear regression model in each study cohort.
We computed all these parameters using a weighted sum.
In MAS5.0, each probe was adjusted using a weighted average.
We also measured disagreement using a weighted kappa.
Arthritis scores were determined using a weighted criterion (Chondrex, Inc).
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