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Reviewer 3: Muir et al. identified a number of novel substrates for Ypk1 kinase using a very elegant genome-wide screen combined with an in vitro Ypk1 kinase assay.
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The group that developed the system originally used a very elegant system to identify the bulge cells of the skin as the quiescent GFP label-retaining population in this organ [6] and these cells have subsequently been characterized as skin stem cells [8].
This problem was also encountered by Madic et al. 30, who used a very elegant and highly mutation-specific PCR method to detect ctDNA in 20 of 21 patients with metastatic uveal melanoma and known GNA11 or GNAQ mutations 2012.
The authors also show that maternal expression of HP1E does not rescue the PEL phenotype, and use a very elegant genetic experiment to show that the embryonic mitotic defects are specifically due to failure to segregate the paternal chromosomes.
As well as serving them with spaghetti, we do a risotto using a very fine, elegant rice, superfino carnaroli.
On the other hand, a new model for coordination based on communication channels (Reo) is also emerging, and we argue it also can be used to describe component protocols in a very elegant way.
A very elegant recent paper using a clean myostatin knock-out system demonstrated that GDF11 levels are 500 times less than that of myostatin or activin, thus precluding any competitiveness for the same receptor complexes and arguing against physiological modulation of pSmad2/3 signaling by GDF11 when myostatin, activin or TGF-beta1 are present [ 48].
Consider using metallic card (gold or silver) for a very elegant look, or match the colors that are your favorites, or your recipient's favorites.
If you have a very romantic bedroom, this can be a very elegant use for vintage lace.
There's a very elegant moment, when he uses his unexpected knowledge of orchids to further the investigation.
"A very elegant, middle-aged black woman used that word in my presence last week," he added.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com