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Children's F&V liking was measured using a validated tasting method.
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Thus, as an exploratory endpoint, self-perceived taste and smell functions were assessed using a validated questionnaire that has been used to evaluate chemosensory functions in AIDS patients [ 34].
Participants provided information on the frequency of dyspeptic symptoms experienced in the previous three months, including heartburn ("a burning or ache behind the sternum not due to heart trouble") and acid regurgitation ("a very sour or acid tasting fluid at the back of the throat") using a validated questionnaire [ 3].
On the persistence of self-reported taste and smell abnormalities as measured by the CSC scores obtained using a validated questionnaire, our results are consistent with previous findings.
Plasma samples were analysed using a validated analytical method.
Toxicokinetics were determined using a validated dual-analyte bioanalytical method.
Psychological distress was measured using a validated five-item, short-version instrument, the SCL-5.
One can notice that the only author using a validated questionnaire was Hagen [14].
Two clinicians scored each CXR for the degree of pulmonary oedema, using a validated method.
Furthermore, we prospectively evaluated patients using a validated outcome instrument with an intensive follow-up.
Resource use was measured using a validated questionnaire.
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