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Cerebral atrophy was assessed using a validated linear cerebral MRI measure, the intercaudate ratio (ICR), for 755 patients.
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One strength of our study is that we measured FoF using a validated questionnaire, which allowed for objective, linear scaling of responses to questions about fear during tasks of varying difficulty [ 29].
Plasma samples were analysed using a validated liquid chromatography/electrospray ionisation-tandem mass spectrometry method that generated a linear response over the concentration ranges of 10 2000 ng/ml and 1000 200 000 ng/ml (Latz et al, 2006).
We predicted concurrent and historical serum PFOA concentrations using a validated environmental, exposure, and pharmacokinetic model based on individual residential histories, and used linear regression to estimate the association between eGFR and measured and predicted serum PFOA concentrations.
Plasma samples were analysed using a validated analytical method.
Toxicokinetics were determined using a validated dual-analyte bioanalytical method.
Using a validated FE modelling technique, a comprehensive parametric study was carried out.
Psychological distress was measured using a validated five-item, short-version instrument, the SCL-5.
We induced tonic pain using a validated cold pressor test (CPT) [14, 15, 21].
Genotyping of the IRP SNPs was conducted using a validated Taqman-based method.
One can notice that the only author using a validated questionnaire was Hagen [14].
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