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This study was designed, using a unique cell model system, to gain insight into the molecular events of anticancer agent-induced cardiomyocyte injury.
Using a unique cell culture system developed by Stampfer and co-author Garbe, both of whom are also with Berkeley Lab's Life Sciences Division, LaBarge and his colleagues were able to generate a large collection of normal HMEC strains derived from primary tissue in women aged 16 to 91 years.
In this study, we have analysed the dynamics of chromosomal instability and chemosensitivity during glioblastoma progression using a unique cell model comprising three cell lines derived from surgery specimens of a long-term surviving glioblastoma patient.
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Using an unique cell line that expresses two different target antigens, we demonstrated a clear advantage of an internalising over a non-internalising MAb-dye conjugate in terms of phototoxic efficacy.
The miscibility and the kinetics of pressure-induced phase separation in solutions of poly(ε-caprolactone) (PCL) in acetone + CO2 binary fluid mixtures have been studied at pressures up to 28 MPa and temperatures up to 410 K using a unique high pressure view-cell equipped with a dual set of pistons and dual set of sapphire windows.
We report here on the development of a novel high throughput assay for proteasome inhibition using a unique, highly sensitive live-cell screening, based on the cytoplasm-to-nucleus translocation of a fluorescent proteasome inhibition reporter (PIR) protein, consisting of nuclear localization signal-deficient p53 derivative.
In this study, we induced cancer stem-like cells from hepatocellular carcinoma (HCC) cell lines using a unique medium, and examined their potential for resistance to anti-cancer drugs.
In this setting, up to 27 different T-cell specificities can be identified in a single cell sample, using a unique two-color code for each pMHC specificity as reported previously (18).
Tc toxins secrete toxic enzymes into host cells using a unique syringe-like injection mechanism.
The typical life cycle of microsporidia involves environmental dissemination in the form of a resistant spore, which is able to infect suitable host cells using a unique apparatus termed the polar tube.
By using data structures and computational logic that best utilizes currently available processing architectures, a cognitive map is created using a unique multimodal source model for place cell activation.
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