Sentence examples for using a triple transgenic from inspiring English sources
Using a triple transgenic mouse reporter system, Kim et al. demonstrated that EMT plays an important role during lung fibrogenesis and may be more widespread than previously thought [13].
To test if let-7 suppression is specifically required for MYC's oncogenic program, we simultaneously overexpressed let-7g and MYC using a triple transgenic, liver-specific, tet-off model.
We used a triple transgenic line designated as CF (for control Flp).
We used a triple transgenic mouse model lacking two isoforms of P-glycoprotein (Mdr1a/1b) and the Bcrp.
A molecular pairlist was generated using a triple-range cutoff.
A subsequent study using the sirtuin inhibitor nicotinamide found that tau phosphorylation is ameliorated in a triple transgenic model of AD.
Another AD mouse model, a triple transgenic mouse (TauPS2APP) does show a loss of GABAergic interneurons in the hippocampus of aged mutant mice compared to WT mice [ 47].
In a triple transgenic model of AD (3 × Tg-AD), we found a significant increase in activated microglia at 12 (by 111%) and 18 (by 88%) months of age when compared with non-transgenic (non-Tg) controls.
In a triple transgenic mouse model, Aβ-42 led to loss of myelin integrity and increased apoptotic cell death of mouse oligodendrocyte precursor cells in vitro, an effect that was reversed through the use of a viral vector-conjugated Aβ-42 specific intracellular antibody [ 58].
In this paper, we have performed an in-depth analysis of astroglial morphology in the EC by measuring the surface and volume of the GFAP (glial fibrillary acidic protein) profiles in a triple transgenic mouse model of AD [3xTg-AD (triple transgenic mice of AD)].
