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Recent report using a triple combination PENTOCLO: PTX-VitE and clodronate; a biphosphonate active against macrophages also allows successful healing of severe osteoradionecrosis [ 44] and reduction of neurological symptoms associated with radiation-induced plexopathies [ 45].
Membrane expression of chemokine receptors was assessed by flow cytometry using a triple combination of monoclonal antibodies: BDCA2-FITC (Miltenyi Biotec, Paris, France); and HLA-DR-PerCp; and CCR2-PE or CCR5-PE or CCR7-PE or CXCR3-PE or CXCR4-PE (BD Biosciences).
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The new treatment options include biologic disease-modifying antirheumatic drugs (DMARDs) [ 3] and the use of a triple combination of synthetic DMARDs [ 5].
21– 23 In light of this, currently available evidence supports the conclusion that the use of a triple combination with palonosetron has the potential to maximize the control of delayed CINV associated with cisplatin or AC without any increase in the complexity of antiemetic regimen.
The anti-angiogenic and invasion-inhibiting effects of a triple combination therapy can be assessed non-invasively with CEUS using the "flash replenishment" (FR) method.
In addition, each of three possible double combination therapies and a triple combination therapy was applied.
2. Use a triple nod.
A favorable risk-benefit ratio was also observed in a previous study that used this triple combination in TTH, albeit with a lower dose of caffeine (50 mg) [15].
Phase 3 trials have been completed in adults with genotype 1 HCV using triple combination PEG-IFN, ribavirin and the protease inhibitors telapravir or boceprevir.
In this cohort, however, 37 % were using triple combination therapy (MTX, sulfasalazine and hydroxychloroquine), as compared with 0.8%% in Norway.
The overall safety and tolerability of vildagliptin was similar to placebo when used in triple combination with metformin and SU (Table 2).
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