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Single carbon atoms in graphene are typically observed with a S/N ratio of 2 at 80 kV using a total dose of ~20,000 e/Å2 [30].
In view of the impressive results obtained by Nigro and colleagues in 45 patients using a total dose of radiation of 30 Gy, we designed an institutional protocol taking into account the needs of this patient group and evaluated the toxicity and outcome using a total dose of 30 Gy of radiation delivered using an involved field approach with reduced dose concurrent 5-FU.
These results have led to CRT (using a total dose of radiation of at least 50 Gy combined with 5-FU and MMC) being established as the primary treatment of anal cancer.
52 The total oral dose and dose regimens for paracetamol varied across trials, with 10 trials using a total dose of 3900-4000 mg/dandand three trials using 3000 mg/day (table 1).
In a subsequent trial at the same institution that compared 3D-CRT and IMRT using a total dose of 81 Gy, the rate of rectal toxicity of IMRT was significantly lower than that of 3D-CRT (2% vs 14%) (Zelefsky et al, 2001).
Nihei et al. [45] applied proton therapy to treat 36 patients with stage I NSCLC using a total dose of 70 94 Cobalt gray equivalents (CGE) delivered in 20 fractions and found similarly high rates of local control (92.6%) and OS (81%) at 2 years.
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During the third treatment week until the end of week 23 of the trial the patient is allowed to use a total dose of 1.000 mg Diclofenac (max. dose 150 mg/day) or a total dose of 175 mg Rofecoxib (max. dose 25 mg/day).
However, earlier high-dose, randomized [ 74] or retrospective trials [ 74, 76] and small, retrospective trials using a total rATG dose of ≤7.5 mg/kg [ 75, 149], have not reported a lower rejection rate compared with IL-2RA induction.
AYVV data was collected on an FEI Titan Krios (Astbury Biostructure Laboratory, University of Leeds) EM at 300 kV, using a total electron dose of 110 e-/Å2 and a magnification of 75,000 × .
Immunizations were scheduled at 0, 1, and 6 months using a total peptide dose of 1 or 4 mg.
Polyethylene components were defined as highly crosslinked when intentionally treated using a total radiation dose ranging from 50 to 105 kGy (Kurtz et al. 2002).
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