Sentence examples for using a targeted sirna from inspiring English sources
Moreover, knockdown of FKBPL using a targeted siRNA approach dramatically increases both ER and cathepsin D protein levels and cell resistance to tamoxifen.
To study the possible role of NOX4 in the RMF-EG-mediated stimulus on MCF-7 migration, we used a targeted knockdown by siRNA approach to downregulate the enzyme expression.
In order to identify DNA repair pathways required for HIV infection, we conducted a targeted siRNA screen using 232 siRNA pools for genes associated with DNA repair.
We screened a targeted siRNA library including 480 siRNAs directed against 240 DNA repair/damage response genes (Qiagen DNA repair subset v2.0).
The effect of CRT5 is therefore strikingly similar to the effect of GF109203X, which, in combination with SB203580, also completely abrogated HSP27 Ser phosphorylation, and also similar to the inhibitory effects of PKD knockdown using targeted siRNA, as previously reported by us [ 10].
It has been shown using targeted siRNA sequences that knockdown of EphB4 in prostate cancer causes a significant reduction in cell motility in vitro and tumor growth in vivo [ 5].
SGK in EE2 ECs was silenced using targeted siRNA.
Using targeted siRNA, 51.2% of them proved to be dengue host factors in humans [ 7].
As in previous studies, we knocked down HDAC6 using targeted siRNA in H929 cells.
Gene knockdown of snail and slug was done using targeted siRNA.
