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Ferric protein was reduced using a system adapted from an earlier study [61] in an Eppendorf sparged with N2.
The quality of tagging for solid residue and fluid was scored using a system adapted from Lefere at al. [ 9] and assigned for supine and prone positions combined for each colonic segment.
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The baseline CT scan was provided to the CT core lab for analysis using a modification of the system used in the NETT study, a system adapted from prior work by Goddard et al[ 13], Bergin et al[ 14], and Bankier at al[ 12].
Most of the literature recommends constructing multiple-choice questions with only one correct answer [ 29]; still, the model we used is considered adequate when using a scoring system adapted to multiple answers [ 27].
Each primary and secondary outcome was evaluated for specificity, using a classification system adapted from the system used by Zarin et al in their assessment of quality of outcomes [33].
Response was evaluated using a grading system adapted from Mandard and establishing an average and a maximal percentual representation of residual cancer cells in the cell population detected in 10 examined slices of formalin-fixed and paraffin-embedded primary tumors.
Systemic maximum toxicity was evaluated using a grading system adapted from the WHO.
The joints were histologically graded by a pathologist (SML), who was blind to the treatment groups, using a scoring system adapted from previous work [ 13].
Because this subset of experiments was analysed using an HPLC system adapted to detect only DA (Becker & Cha, 1989) we could not examine the effect of nomifensine on NE levels.
In contrast, a non-invasive pulsedensitometric method uses a transcutaneous system adapted from pulse oxymetry and a peripheral or central venous access for ICG injection.
We used a rating system adapted from Anderson and Sharpe [ 13] (see Additional file 2), which evaluated the impact of various types of intervention on the behavior change of health care workers, in line with our review.
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