For example, using a surgical wound model, McLoughlin et al [37] reported that in the absence of IFN-γ, a decreased S. aureus burden was observed at the site of infection.
Using a mouse surgical model of post-traumatic osteoarthritis (OA), we sought to determine if muscle function is altered following acute joint injury and whether this relates to OA progression.
Therefore, we analyzed the effects of A-928605 in a surgical model of neuroblastoma using SK-N-FI cells injected into the renal subcapsule.
We therefore designed a surgical model for cervical heterotopic pancreas transplantation using a cuff technique.
Herein, we have identified a novel methodology for evaluating neoadjuvant efficacy using a spontaneous surgical metastasis model and show how it can be used to explain differential efficacies of VEGF pathway inhibitors seen preclinically and clinically.
In the present study, we have performed a detailed analysis of the contribution of MyoD-lineage cells to bone repair in the mouse tibia using a number of surgical models.
Evidence of endothelial activation following tourniquet-induced ischaemia- reperfusion injury has previously been documented using a non-surgical human model [2], [21].
Finally, we induced cartilage destruction in mice using the DMM surgical model.
Surgical simulation and preparation of the surgical device were performed using a 3D model.
