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The network was expanded by incorporating literature-curated and evolutionarily conserved interactions, and 770 predominantly novel PPIs were identified using a stringent yeast two-hybrid screen.
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The identification of CNV regions (CNVRs) was performed by using a stringent procedure.
We report these results using a stringent family-wise error (FWE) volume-corrected threshold of P<0.05.
ClCE8 homologs were retrieved from the NCBInr protein database using a stringent E value of 1e-50.
The hit rate using a stringent cutoff of 2-fold inhibition (activity of <0.5) was 0.05%.
Using a stringent filtering method, we identified 3.1 million SNPs, 193 thousand INDELs, and 282 CNVs.
For the rapamycin and viral oncogene data, we used a stringent p-value cutoff of 0.001; for the rest of the yeast stress conditions, we used a p-value cutoff of 0.05 due to the smaller number of samples.
We used a stringent SVM score threshold of 0.5 to reduce the number of false positives.
We use a stringent threshold (score > 0.9999) to assign a sample as a VINO.
We used a stringent code list to diagnose COPD and exacerbations.
We used a stringent cutoff for defining seropositivity, which probably underestimated the seroprevalence in our population.
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CEO of Professional Science Editing for Scientists @ prosciediting.com