The proposed method was developed and optimized using a statistical design of experiment approach.
The spray drying process was optimised using a statistical design of experiment and by evaluating powder characteristics upon systematic variation of the formulation parameters.
Using a statistical design of experiment (DoE) technique this paper has investigated the effects and interactions on equilibrium drug solubility of seven typical SIF components (sodium taurocholate, lecithin, sodium phosphate, sodium chloride, pH, pancreatin and sodium oleate) within concentration ranges relevant to human intestinal fluid values.
In this work, the CVD of BN was investigated using a statistical design of experiments (DOE) approach.
Statistical models established using a statistical design of experiments indicate that the W/C has greater effect on changes in minislump flow, washout, and RCS than the concentrations of HRWR and AWA.
These CPPs were prioritized using a process failure mode, effects, and criticality analysis and their critical impact on the CQAs was experimentally confirmed using a statistical design of experiments.
To this end the percentage of porosity as a function of both the amount of set-retarding admixture and the kneading water needed was assessed using a statistical design of experiments (DoE) approach.
Test conditions were determined using a statistical Design of Experiments approach which allows the experimenter to probe a wide range of variable factors with a comparatively low number of experimental trials.
The catalytic performance for steam reforming of methanol over 5 wt.% Au/CuO CeO2 catalysts prepared by deposition precipitation was investigated using a statistical set of experiments in order to optimize the methanol conversion with minimal carbon monoxide (CO) selectivity.
In this work, the efficiency of struvite precipitation from source separated human urine and struvite crystals size were analyzed using three different Mg2+ sources (MgCl2, Mg(OH 2 and MgO), individually evaluated using a statistical design of experiments to assess the combined effect of Mg2+ P molar ratio (1 1, 1.5 1 and 2 1) and stirring speed (30, 45 and 60 rpm).
