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To evaluate serial serum C-reactive protein (CRP) levels for diagnosis of neonatal infection.A regional intensive care nursery and two community intensive care nurseries.All neonates treated for suspected bacterial infection were prospectively evaluated using a standardized clinical pathway.
The participants were examined using a standardized clinical examination [ 40].
The patients were also characterised at the Centre for Pediatrics and Adolescent Medicine, Freiburg, Germany, using a standardized clinical protocol.
Using a standardized clinical protocol (12), children were positioned in a knee-to-knee position with a parent or family member helping to hold the child.
The U-NGAL assays were performed using a standardized clinical platform (ARCHITECT analyzer; Abbott Diagnostics, Abbott Park, IL, USA) as previously described [ 33].
CAVA is a freely available tool that provides rapid, robust, high-throughput clinical annotation of NGS data, using a standardized clinical sequencing nomenclature.
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The pediatric otolaryngologist used a standardized clinical form that elicited all of this clinical information by history and/or by documentation from the primary care provider.
Harris-Hayes and van Dillen found overall percent agreement on the classification assigned to be 83% with kappa = 0.75 (95% confidence interval = 0.51-0.99; P <.0001) and concluded that inter-tester reliability of classification of patients with LBP when therapists use a standardized clinical examination based on the Movement System Impairment classification system is substantial [ 50].
Demographic and clinical characteristics were extracted from the child's medical file using a standardized paper clinical extraction tool and entered into REDCap.
Data were collected prospectively by the clinician administering ketamine in all cases of ESM-Ketamine use at study facilities using a standardized ESM-Ketamine clinical record form.
Using a standardized form, the clinical and laboratory data leading to the diagnosis were collected for each case.
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