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The strength of synchronization of regular patterns was measured using a standard score, the Z score of the amplitude of the central peak of the cross-correlogram [21]: Z = (Nc−Ne)/ SDe), with Nc the number of spikes in the central peak (bin = 5 ms), Ne the mean number of spikes in a 2 sec window between −1 and 1 sec, and SDe its standard deviation.
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Using a standard scoring method, we can calculate the general score of PCS and MCS.
Severity of mucosal inflammation was graded using a standard scoring system [ 28, 30].
Each study was also assigned a quality score of +1, 0, or -1 using a standard scoring system.
The answers are then assessed using a standard scoring template with points awarded for key components of each answer.
All had joint activity scores of at least 15 using a standard scoring system [ 11] based on that used in pediatric rheumatology clinical trials [ 12].
Body weight was assessed daily, and colon length and weight on day 12. Blinded histological assessment was made using a standard scoring system (Dieleman et al., 1998), and cytokine expression quantified by qPCR from sections of paraffin-embedded colons.
Body weight was assessed daily, and colon length and weight on day 12. Blinded histological assessment was performed using a standard scoring system (Dieleman et al., 1998 ) and cytokine expression was assessed by quantitative RT-PCR (TaqMan predesigned qPCR assays, Applied Biosciences) using mRNA extracted from sections of paraffin-embedded colons using an RNEasy FFPE kit (QIAGEN).
We documented demographics, clinical characteristics, HIV status, M.tb exposure (using a standard contact score) and M.tb infection status (TST > = 10 mm).
Arthritis severity was determined using a standard visual scoring system based on the degree of swelling and redness ranging from 0 to 4 for each paw.
After determination of motif (word-matching in the nucleotide string) or module (word-matching separated by flexible gaps) abundance, enrichment or depletion in the experimental dataset compared to the randomized background population is calculated using a standard Z-score.
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