The least-squares (LS) coefficient can be used to estimate how well the given distance matrix D, obtained from the multiple sequence alignment A using a specific sequence-to-distance transformation, approximates the patristic distance (i.e., additive distance or tree metric) Δ between the leaves of the phylogenetic tree T obtained from D using the selected tree-building algorithm.
For any particular application using a specific sequencing method, optimisation of the SNP- and indel-calling algorithm would always be recommended.
In addition, all yeasts appear to have Dam1-DASH complex, regardless of whether they use a specific sequence to identify the location of the kinetochore, as in S. cerevisiae, or if they have a regional kinetochore assembly process, as in S. pombe [12].
Based on these results, we recommend that global shotgun lipidomic experiments employing chemical sulfation of sterols use a specific sequence of MS analyses where the analysis of sulfated samples is scheduled at the end of all other analyses in order not to compromise analytical sensitivity (Fig. 2).
MSL, JHC and YYL are inventors on a patent submission entitled: A method for Protein Translocating into Nucleus Using A Specific Peptide Sequence for.
PCR amplification was performed using a specific primer (sequence available upon request) designed within the fragment in combination with a degenerate primer pointing outward of either the 5' or the 3' edge of the element (see Additional file 3 for details).
Using a specific input-restructuring sequence, a new VLSI algorithm and architecture have been derived for a high throughput memory-based systolic array VLSI implementation of a discrete cosine transform.
To address this issue we used a knockdown approach using a specific RNAi target sequence (see Materials and Methods).
At mass spawning aggregations of giant cuttlefish (Sepia apama) in the Upper Spencer Gulf in South Australia, a wild female Indo-Pacific bottlenose dolphin (Tursiops aduncus) was observed and recorded repeatedly catching, killing and preparing cuttlefish for consumption using a specific and ordered sequence of behaviours.
