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Myogenic progenitor cells were quantified using a specific marker, an antibody to paired box protein 7 (Pax-7).
Using a specific marker for neutrophils, Ly6G, infiltrating neutrophils were detected in the G3 mTerc−/− brain parenchyma (Fig. 5E,F).
In fact, dissociation between inflammation and blood brain barrier disturbance in multiple sclerosis patients has been described by using a specific marker, which selectively stained leaky endothelial cells in brain vessels (Hochmeister et al., 2006).
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Since Iba1 does not clearly discern between resident and activated microglia, we used a specific marker for the proinflammatory phenotype of microglia, CD16/32 [ 30– 30].
As a putative ER-targeting protein, OsFKBP15-1-GFP protein seemed to be localized in the ER, but we were unable to use a specific marker protein in this study.
To shed further light in this issue, and considering that we did not find differences in terms of density of Iba1-labeled microglia between Cre LysMCasp8 fl/fl mice and Casp8 fl/fl mice in response to intranigral LPS, we decided to use a specific marker of M1 proinflammatory microglia, CD16/32 [ 3, 30, 32].
The application of PAR% was evaluated for benefit of community-based efforts to prevent disease using a specific cancer marker by Wacholder [ 33].
Loss of brain volume in HD is also accompanied by a significant increase in astrocyte number, as shown when using a specific immune-marker GFAP.
Schweitzer, R. et al. Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments.
The formation of dextrorphan (DOR) from DEX was used as a specific marker of CYP2D6 activity.
Rabbit anti-human calnexin (Sigma-Aldrich, France) was used as a specific marker of reticulum in caco-2 cells.
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