Sentence examples for using a single concentration from inspiring English sources
Using a single concentration (300 μM) we identified 46 novel leads from a library of 1443 fragments (hit rate = 3.2%).
We then tested the Cav3 channel subtype selectivity of compound 9 using a single concentration of 3 μM.
In the preliminary screening all 212 endophytic extracts were tested for BACE1 inhibition using a single concentration of 1000 μg/ml.
(E ) Binding assays were performed on Axl-expressing MEFs using a single concentration of I-labeled full-length rmGas6 in the presence of increasing concentrations of either unlabeled full-length rmGas6 (black) or Gla-less rmGas6 (red).
The experiments were repeated on cartilage obtained from the hips of four other patients using a single concentration of 0.1 μM of the respective TIMPs (n=5, including the previous patient).
These values are significant when compared to those obtained in previous studies [ 18], which have shown inhibition values of 17 plant extracts ranging from 9 to 81% using a single concentration of 1 mg/mL.
Because of their potency compared with isolated Caf1 (IC50 values in the range of 100 140 μM; Figure 4A), we used a single concentration of 300 μM for each compound.
Beside, here, we used a single concentration of IL-1β (1 ng/ml) whereas in the majority of previous study showing NFkB activation in tenocytes, IL-1β was used at higher concentration [ 48– 50].
A standard PK equation-based approach using 2 concentrations and a population PK model-based approach using a single trough concentration yielded unbiased and precise AUC estimates.
Therefore, the results of the present study using a single ETOH concentration and an operant paradigm resemble the data for the repeated deprivations with access to multiple ETOH concentrations, because both the magnitude and the duration of the ADE were increased with repeated deprivations.
This study evaluated precision and bias in estimating vancomycin AUCs obtained either from a population pharmacokinetic (PK) model by using a single trough concentration or from standard PK equation-based 2-point monitoring approach.
