Sentence examples for using a single alignment from inspiring English sources
At stage two, the structures were refined with RDC restraints using a single alignment tensor.
First, instead of using a single pairwise alignment score, we align two proteins with respect to different evolutionary, structural and physicochemical properties.
The parameters of the HMM can be initialised by using a single sequence or a pre-existing alignment.
Using a single sample as an example, this figure shows the alignment position of each tRNA.
Alignments were performed on a Hewlett-Packard (HP) AlphaServer GS1280 system, using a single 1.15 GHz processor.
Then the two resulting alignments were combined into a single alignment using the "profile alignment" option of ClustalX [ 28].
A subset of the recruited sequences from each of the represented class C subfamilies (GABAB, metabotropic glutamate, calcium-sensing, vomeronasal, pheromone, odorant and taste receptors) in addition to predicted and hypothetical proteins were selected based on the lowest E-values per NCBI taxa ID and included in a single alignment using MUSCLE [ 54].
A set of single copy gene families present in all genomes were then selected and aligned using MUSCLE [46], and concatenated into a single alignment consisting of a total of 196,481 amino acid positions (476 genes/ORFs, see Table S4).
This study shows that a small number of high-quality, all atom, and minimized models are sufficient to reliably evaluate a single alignment when using a sensitive and accurate scoring function.
In the case of MetaPSICOV, however, a single alignment is used, but is supplemented by an array of features which describe the local and global quality of the given alignment.
