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Numerous further questions about natural selection can be addressed using a simple population-genetic model.
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Using a simple population genetic model, we show that a sexually dimorphic genetic architecture for fitness- and disease-related phenotypes readily emerges when mutational effects are imperfectly correlated between the sexes.
A potential mechanism underpinning this finding was explored using a simple population dynamic model.
We develop a simple population genetic model of disease susceptibility and evaluate it using a biologically plausible empirically based distribution of fitness effects among contributing mutations.
We therefore developed a simple population genetic model that characterizes the interaction between sex-specific selection among mutations and the genetic basis of fitness variability within each sex.
We tested the generality of this prediction using a simple, but realistic genetic model.
Analysis using simple population genetic models that do not consider the ecological complexity of the natural populations is the first step of the theoretical assessment.
We recruited a convenience sample from this population, using a simple random method.
Enumeration of new QTLs in this population would therefore be impossible using a simple mapping method.
Table 3 Attribute selector AS Description Genetic Search GSS) Uses a simple genetic algorithm.
One is to use a simple genetic risk score based on the number of risk alleles carried.
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CEO of Professional Science Editing for Scientists @ prosciediting.com