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Using a significance analysis of microarrays (SAM) with a 2-fold ratio cut off and a false discovery rate (FDR) <5%, we compared whole blood and CD34+ HSPC to the group of solid tissues samples.
Statistical analysis was performed using a Significance Analysis of Microarrays (SAM) [ 32] unpaired contrast, available through the TM4 software package (JCVI).
To identify the most relevant differentially-expressed genes, we compared the C, PB and V berry transcriptomes at each time point using a Significance Analysis of Microarrays (SAM) unpaired comparison with a false discovery rate of 2%.
A total of 194 breast tumors were analyzed by clustering analysis using a modified version of the 'SAM264' gene list [ 18]; the 'SAM264' gene set is the set of genes that were associated with survival as identified using a Significance Analysis of Microarray analysis and contained 10 of the 21 genes sequenced.
Significant adjustments in muscle transcript expression following a single bout of endurance exercise and training between carriers and non-carriers of the ACE I-allele were evaluated from normalized values using a Significance Analysis of Microarrays test (SAM) running as an applet in Microsoft Excel software (Tusher et al. 2001).
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The bottom row of Table 1 shows that a combined analysis using a significance level of 10-4 achievesignificanceance level similar than the 3-group strategy, and a greater power.
In a censored two group class comparison analysis, using a significance level of P-values<0.01 (q<0.05), 148 miRNAs were differentially expressed between the CSCC and cervical controls.
Using a significance threshold of 1.7, PAM analysis produced a set of 15 genes to serve as a classifier (Supplementary Table SIV).
The intention was to enter independent variables with statistically significant odds ratios at the 10% level in the univariable regression analyses into a multivariable regression analysis using a significance level of 5%.
Sites under selection with the M8 model were identified using Bayes empirical Bayes (BEB) analysis using a significance cutoff of 0.90 (Anisimova et al. 2002; Yang et al. 2005).
We included all factors found to differ among sub-groups in stratified analysis using a significance level of p ≤ 0.05 of all results in univariate analyses and adjusted for mode of questionnaire administration.
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