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A total of 23 family members (9 affected and 14 unaffected) participated in this study and had a full ocular assessment to document the phenotype, including visual acuity testing, slit-lamp photography, corneal diameter measurement, and axial length measurement using A-scan ultrasonography.
Axial length (AL) and vitreous chamber depth (VCD) were measured using an A-scan ultrasonography (Suoer, 10 MHz; Tianjin, China) under anaesthesia (2% isoflurane in oxygen).
The step response results of the crystalline lens thickness to a target vergence demand (Figs. 10(G) and (H), red lines) are similar to those obtained using continuous high-resolution A-scan ultrasonography [ 3].
The animal specific A-scan ultrasonography was used for the axial length measurement.
A-scan ultrasonography (Aviso, Quantel Medical Inc., France) was used to measure the axial lengths of the eyes.
Increasingly used Partial Coherence Interferometry (PCI) for measuring axial length surpasses in resolution A-scan ultrasonography (0.01 vs 0.1 mm) [ 9, 10].
Axial length, measured by A-scan ultrasonography, is an additional outcome measure.
A-scan ultrasonography (Ophthascan: 7MHz) was performed and axial length and vitreous chamber depths were determined.
The axial length of the eyes was measured by A-scan ultrasonography ODM-1000A/P ODM-1000A/P-MHz transducer.
A possible limitation of the study was less precise measurement of axial elongation with A-scan ultrasonography compared to partial coherence interferometry.
In a previous study we compared the OA-1000 results of axial length and anterior depth with those obtained with the IOLMaster and contact applanation A-scan ultrasonography.
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