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Genotype probabilities were estimated using a restricted implementation of the Elston-Stewart algorithm [ 22], restricted in that it operated only on half-sib families.
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The genetic and residual variance components, σg and σe, are estimated using an efficient implementation of restricted maximum likelihood in EMMA.
A transformation should also not impose additional constraints without a good justification, as these will restrict implementation choices.
New approaches to flood protection using natural water retention measures offer increased opportunities for floodplain restoration, but conflicting societal needs and legal frameworks may restrict implementation.
All possible transformation size-restricted MMPs and RECAP-MMPs were calculated using an in-house implementation of the algorithm by Hussain and Rea that utilizes the OpenEye toolkit.
Advanced directives restricting implementation of the protocol.
V(D J assignment and mutation identification was performed using an implementation of SoDA42.
Geodesic computations were performed using an implementation of the exact discrete geodesic algorithm66,71.
Bright spots were automatically detected using an implementation of the difference of Gaussians method and thresholding.
The algorithm is evaluated using an inhouse C++ implementation.
Number of iterations were restricted using a counter (Fig. 3).
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