Sentence examples for using a reference population from inspiring English sources

A potentially attractive alternative option would be to impute based on the 1000 Genomes Project; however, this has the drawbacks of using a reference population that does not necessarily match the disease status and LD pattern of the study population.

Imputation of crossbred animals using a reference population that included only Yorkshire pigs resulted in a larger decline in accuracies than using a reference population that included Landrace pigs only.

For patient diagnostic categorisation, lumbar spine and femoral neck BMD T-scores were calculated using a reference population previously described.

Our results demonstrate that using a reference population of one breed to predict GEBV of another breed gave low GEBV accuracies or equal to zero.

For across-population genomic prediction, breeding values are predicted for individuals using a reference population of individuals from one or more different populations.

The SMR is defined as the ratio of the observed number of events, for example deaths, to the expected number estimated using a reference population.

However, most studies evaluating patient-reported outcomes do not use a reference population or pre-injury values.

Thus, we conclude that having a genotyped sire is not the main cause of the differences in imputation accuracies for crossbred animals when imputation used a reference population that consisted of Landrace pigs only compared to Yorkshire pigs only.

We used a reference population of 1000, 2000 or 3000 purebred Merinos of both sexes, which were randomly chosen from a total of more than 4500 purebred Merinos across all resource flocks.

Another possible interpretation of why imputation accuracies for crossbred animals were higher when imputation used a reference population that consisted of Landrace pigs only compared to Yorkshire pigs only is that the Landrace breed contains Yorkshire haplotypes.

When the size of the reference population is very large, it is not necessary to use a reference population that combines the two breeds to impute the genotypes of purebred animals because a within-breed reference population can provide a very high level of imputation accuracy (correct rate ≥ 0.99, correlation ≥ 0.95).