To this end, we have used a rapid molecular technique, restriction site mutation (RSM), to detect low-frequency mutations in the p53 tumour suppressor gene in premalignant Barrett's tissues of cancer-free patients.
We used a rapid molecular conversion assay (protein misfolding cyclic amplification) to test whether brain homogenates from specimens of classical bovine spongiform encephalopathy (BSE), atypical BSE (H-type BSE and L-type BSE), classical scrapie, atypical scrapie, and chronic wasting disease can convert normal human prion protein to the abnormal disease-associated form.
In the present study, we validated a new format of molecular method based on ITS-PCR followed by sequencing to identify common and cryptic Candida species causing candidemia by analyzing fungal DNA in yeast-positive blood culture bottles using a rapid and accurate molecular method.
Our study shows that the use of a rapid molecular diagnostic test for the identification of bacterial and fungal pathogens may lead to a higher rate of early adequate antibiotic therapy in approximately 8% of patients with suspected sepsis.
In order to adequately address the threat of TB, the WHO has taken key steps, particularly in recent years, by promoting various interventions, including the use of a rapid, molecular-based technology for diagnosis of TB [ 27], increased investments in laboratory services, focus on preventive therapy for HIV-infected patients and surveillance of drug resistance.
Alere™ i (Scarborough, Maine, USA) is a rapid molecular diagnostic test using nicking endonuclease amplification reaction, a kind of isothermal amplification, and it allows for differential and qualitative detection of influenza virus type A and B from nasal swab specimens in viral transport medium.
A rapid molecular technique to detect resistance to second-line drugs in MTB using hybridisation analysis on microarrays was developed in this study.
A rapid molecular technique for the detection of resistance to second-line drugs in M. tuberculosis has been developed using hybridisation analysis on microarrays.
Functional binding sites are extracted by a rapid molecular dynamics shaker.
Prognosis in this setting might be improved by earlier presentation to the health services, minimization of referral delays, and accelerating diagnosis by using novel rapid molecular assays, for example [ 23].
