Instead we generate a null distribution for the option bias statistic using a randomisation approach [28].
The significance of these two test statistics was assessed using a randomisation test.
Simple randomisation using a randomisation table (computerised sequence generation) will be used.
The randomisation was performed by a central office using a randomisation schedule.
An independent statistician generated the allocation sequence using a computer randomisation programme (RANDOM, Southampton University).
General practices will be randomly assigned to the intervention or control group using a computerized randomisation programme.
Participants were randomised into either the C-SSB or NC-SSB group using a computer-generated randomisation programme stratified by sex.
Patients are randomised in a 1 1 fashion to either RIC or sham-RIC (control group) stratified by centre and donor type, using an online block randomisation programme.
Randomisation will be performed using a computer programme.
Participants are randomly allocated to one of the three groups using a partial minimisation procedure to adjust the randomisation probabilities between groups to balance important covariates including duration of diabetes, HbA1c, and prior medication using a computer programme (Minim, ).
