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177Lu-DOTATATE/-TOC was prepared using a radiotracer synthesis module (Scintomics, Fürstenfeldbruck, Germany) with minor modifications as described before [15].
Ga-DOTATOC/Ga-DOTATATE was prepared using a modification of the method described by Breeman et al. [ 25] using a radiotracer synthesis module (Scintomics, Fürstenfeldbruck, Germany).
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Holdup and axial dispersion of liquid phase in a catalytic exchange column were investigated by measuring residence time distributions (RTD) using a radiotracer technique.
Fluorination of aromatic compounds by nucleophilic displacement of trimethylanilinium salts by fluoride is a commonly used reaction for radiotracer synthesis.
Radiotracer synthesis was performed using a microlab (GE Healthcare, Solna, Sweden) synthesis module, and all tests for radiochemical identity and purity have been approved before release.
In this study, we have successfully developed the first F labeled non-peptidic bivalent integrin αvβ3 targeting radiotracer using a one step F-AlF/NODA chelation reaction.
The Al(NOTA) chelate is highly efficient for radiosynthesis of 18F radiotracers using a kit formulation.
Bromine-82 as ammonium bromide was used as a radiotracer and about 40 60 MBq activity was used in each run.
To maximize efficiency, we optimize binding affinity assays using a known positive control concomitant with the synthesis of the radiotracer library.
The average radiance versus activity of the radiotracer was plotted for both radiotracers and fitted using a linear regression.
Bromine-82 as p-dibromo biphenyl was used as a radiotracer for measuring RTD of the organic process fluid.
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