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Now it is set to carry out its riskiest, most intricate manoeuvre using a probe that has no rocket landing thrusters or guidance system.
Mitochondrial DNA was quantified using a probe that specifically recognizes the mitochondrial gene MtND2.
To further investigate chromosomal alterations during male meiosis in rsw4, we examined the distribution of centromeres, using a probe that recognizes pericentromeric heterochromatin in A. thaliana [36].
The cellular distribution of prominin-1 transcripts within the eye was investigated in both larval and juvenile axolotl by ISH using a probe that allows the detection of all potential splice variants.
Northern analysis for the region using a probe that is unique to Meg8 cDNA showed that it is expressed highly in the adult mouse brain and skin (Figure 6B).
As Figure 10 shows, Northerns using a probe that would detect both Meg9 and Mirg demonstrate that Meg9/Mirg is widely expressed in many adult mouse tissues with the highest levels being in the brain, skin, and testis.
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Due to the transient nature of ROS, it is important to use a probe that does not accumulate over time, but reflects both the rapid production and decay of ROS in the system.
We used a probe that was able to recognize both mature and pre-miR-134.. Low levels of miR-134 were detectable in unstimulated neurons and KCl led to a robust and specific increase in miR-134 ISH signal, confirming our results obtained with quantitative RT PCR.
We use a probe that we can move along the fiber and which we can track in three-dimensional space with nanometer accuracy.
Most of these probes fluoresce green, and so to view a second signal that occurs in the cell at the same time it's easier to use a probe that fluoresces with a different color, such as red.
To determine the level of genetic chimerism, we used a probe that distinguishes between a wild-type Trp53 allele and the floxed Trp53 F2-10 allele (Jonkers et al, 2001), reflecting the contribution by the host ESCs or cultured ESCs, respectively (supplementary Fig S3).
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