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In a recent study, our group found that septic patients without ARDS ventilated with a protective strategy using a plateau pressure < 30 cmhad had better outcomes and a lower incidence of ARDS than those ventilated without this limit on plateau pressure [28].
However, the strategies for setting PEEP using a plateau pressure or recruitment manoeuvre do not decrease mortality [ 9, 10].
In a recent study, our group found that septic patients without ARDS ventilated with a protective strategy using a plateau pressure < 30 cmhad had better outcomes and a lower incidence of ARDS than those ventilated without this limit on plateau pressure [ 28].
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Utilizing the assumption that the four measurements made on each subject during this study should be equal, the relationship of within-subject variance was described using a quadratic-plateau model as assessed by segmental polynomial (knot) regression.
Only extracts I and V showed concentration dependency under preexposure conditions only, while extracts II, III, and IV showed the same antimutagenic activity at both concentrations used, a possible plateau effect.
The load was applied to the medial tibial plateau using a spherical loader.
The tracer was implanted into loessial soils from the Loess Plateau using a wet soil-tracer mixing procedure.
Next, the medial meniscus was detached from the tibial plateau using a fine cannula and a surgical microscope.
With the left hind limb in a neutral position of 90° of flexion, a 10-N compressive preload was applied to the tibial plateau using a materials testing system (ElectroForce ELF3200; Bose, Framingham, MA, USA) via a custom indenter.
These changes typically include a decrease in the tissue aggregate modulus and an increase in fluid permeability [ 37], which we measured on the medial tibial plateau using a micro-indentation test [ 30].
To make the grafts we made two osteotomies at the shaft of the bones, 8 mm and 16 mm from the tibial plateau, using a fine-toothed circular saw blade mounted on an electric drill.
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