Sentence examples for using a novel gene from inspiring English sources

Using a novel gene clustering strategy we determined pathway relationships from a genome-wide transcriptional dataset of skeletal myoblast differentiation.

Using a novel gene therapy approach, Pastore et al. studied the effect of transcription factor EB (TFEB), a master gene that regulates autophagy and lysosomal gene expression (Pastore et al., 2013).

C. Explore gene-gene interactions using a novel gene-based statistical approach.

This will involve: conducting conditional tests to identify the causal genetic variant among multiple correlated signals; testing whether the effect of PTSD genetic risk variants is moderated by age of first trauma, trauma type, and trauma severity; and exploring gene-gene interactions using a novel gene-based statistical approach.

We therefore used a novel gene expression profiling approach (3SEQ) that uses next generation sequencing of RNA fragments purified by oligo-dT selection from FFPE material (Additional file 12).

We introduce an exploratory visualization tool, named Pipit, which uses a novel gene-centric visual encoding to examine how gene structures individually are affected by structural variants.

In this regard Gopalan et al. (2004) found NP-based gene therapy to be effective in systemic gene treatment of lung cancer using a novel tumor suppressor gene, FUS1.

In the present study, we established a novel method to visualize neural activity in the honeybee brain using a novel immediate early gene, kakusei, as a marker of neural activity.

We analyzed a Swedish Watchful Waiting cohort with up to 30 years of clinical follow up using a novel method for gene expression profiling.

DOI: http://dx.doi.org/10.7554/eLife.01715.019 Using a novel in vivo gene replacement strategy at a large CNS synapse, the calyx of Held, we show that PKC phosphorylation of the presynaptic protein Munc18-1 is critically important for PTP, a form of short-term enhancement observed at many CNS synapses.

Using a novel metric called gene-strand skew, where a value of 1 indicates all exons are coded on one DNA strand while a value of 0 indicates exons are equally distributed on both strands, we show that G. sulphuraria has a mitochondrial gene-strand skew of 0.88.