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Using a novel conformational fingerprinting approach for ACE, we demonstrated that mutant ACE was selectively denatured.
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Plasma β-FXIIa was measured using a novel FXIIa ELISA that employs mAb (monoclonal antibody) 201/9 which binds to conformational epitopes on the heavy chain of β-FXIIa and exhibits no cross-reactivity with FXII zymogen or FXIIa inhibitor complexes [ 21].
Using a novel derivatization reagent and mass spectrometry based analysis strategy to monitor changes in the covalent modification rates of lysine residues between native and H2O2-induced oxidized forms of CN, multiple regions within the protein complex that undergo significant conformational perturbation upon oxidative modification have been identified.
S139/1 is a murine mAb isolated from mice immunized intranasally with H3 virus and recognizes a novel conformational epitope near the RBS.
Both snapshots of the oxidized KtzI enzyme suggest a novel conformational change for a protein-bound flavin molecule; however, they are also quite different from one another.
Glycolipid transfer protein is the prototypical and founding member of the new GLTP superfamily distinguished by a novel conformational fold and glycolipid binding motif.
During 2009 2010, we analyzed conformational stability of PrPSc from sheep TSE isolates by using a conformational stability and solubility assay (CSSA) that we developed (14 ).
The shift in peak potentials is explained using an electrochemically stimulated conformational relaxation model.
However, a novel conformation of Ub and the observed conformational transition could result in a less stable molecule.
Duarte, C. M., Wadley, L. M. & Pyle, A. M. RNA structure comparison, motif search and discovery using a reduced representation of RNA conformational space.
Duarte, C.M., Wadley, L. & Pyle, A.M. RNA structure comparison, motif search and discovery using a reduced representation of RNA conformational space.
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