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Therefore a given mRNA transcript was considered as differentially expressed in the comparison of any two samples if the difference gave a P value of ≤0.05 in the Welch ANOVA parametric test, using a multiple test correction (Benjamini and Hochberg False Discovery Rate).
Transcripts showing enriched transcription in each of the four body parts were determined using a multiple test correction significance cut-off of p ≤0.05 for both the resistant and susceptible strains.
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Non-inferiority of lumiracoxib for the primary outcome variable (1-year retention on treatment) was tested by a non-inferiority test comparing pairwise differences using a multiple testing procedure to adjust for multiplicity and a confidence interval (CI) approach with a predefined non-inferiority margin of -10%.
A significant P-value threshold was applied using a multiple testing correction (Bonferroni, P value < 0.05).
Using a multiple testing correction p-value threshold of 2.2x10−6, there were 1584/22374 (7 %) methylation probes that were significantly differentially methylated.
We used a multiple test consisting of three individual tests, which produce a total of eight possible results.
The data were first checked for normality, then differences between selected groups were tested using a multiple t-test.
The means were compared pairwise using a multiple comparison test.
Differences were further analyzed using a multiple range test when ANOVA p < 0.050.
Statistical differences in DNA damage levels between individual dose points were evaluated using a multiple post-hoc test (Newman-Keuls).
We assessed knowledge using a multiple-choice test.
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