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Success using a motif based on the concept of tensegrity, a balance between tension and compression forces, was finally reported in 2009.
Database searches using a motif scanning algorithm [34] (scansite.mit.edu) identified candidate substrates for LRRK2 G2019S that contain sites that most resemble the sequences derived from the two peptide scans (Table 1).
Using a motif discovery approach and ScanProsite analysis, we identified eleven conserved motifs that are present in PIG-A proteins.
The HIV-Host protein interaction network was analyzed for network motifs using a motif detection algorithm implemented in Prolog (see additional files 13, 14, 15 and 16).
In addition, rather than using a motif database as an input, it implements a simple motif count table for each enumerated k-mer for each gene promoter sequence.
The conservative motif containing the Sec residue of an i-gene was analysed by the program using a motif search algorithm like MAME.
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Using a motif-based system developed for this study to identify canonical CEP peptide domains, a total of 916 CEP genes and 1,223 CEP domains were found in angiosperms and for the first time in gymnosperms.
(BLAST allowed us to focus on short identical sequences for a stringent first-pass search of shared functional elements – it is likely that a less stringent search using a motif-finding algorithm may reveal additional motifs).
Ailes used a motif from talk radio to come up with America's Talking, but was sideswiped by the big guns at NBC when they formed MSNBC in a synergistic partnership with Microsoft, effectively hitting the delete key on much of what Ailes had built.
This is the first instance in which a pathogen has been described to use a motif similar to an ER export signal to ultimately inhibit cellular protein secretion.
This represents a novel approach to antagonize ER/Golgi trafficking, as no other cellular or microbial protein has been described to use a motif similar to an ER export signal to gain access to and antagonize the secretory pathway.
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