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Thus, a milder and different form of CR that increased longevity in normal control mice failed to further increase the lifespan of long-lived GHRKO mice, corroborating our previous findings using a more severe (30%) traditional CR regimen [16].
Lastly, we did not consider other predictive scores (eg, PLAN score, 11 iScore, 12 six simple variable 13 and five simple variable scores 14) for our models primarily due to the following reasons: (1) none of these scores include a cognitive measure; (2) PLAN scores are developed using a more severe functional outcome measure, such as mRS scores of 5 6 at discharge.
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On the other hand, Italy RD used a more severe case cutoff of 2 standard deviations, which may be more comparable to severe RD and severe LI case definitions in ALSPAC.
We have avoided using patients with a more severe category of asthma because these patients are usually on chronic treatment with inhaled corticosteroids and are likely to have an inflammatory infiltrate.
We hypothesized that CAM use associates with a more severe disease in paediatric IBD and JIA populations.
We hypothesized that CAM use associates with a more severe disease in paediatric IBD and JIA.
While antidepressants may have contributed to an increased frailty risk, it is also possible that antidepressant use may reflect a more severe, recurrent, or chronic form of depression.
The patients in the mortality group who had used ED services had a more severe triage (p < 0.001), and higher admission rate (4.9% vs 2.4% compared to the other group, p < 0.001) that could lead to subsequent aggressive interventions and more treatment-related expenditure and greater length of stay in their last 6 months of life.
Using this method, patients with a more severe disease course could be selected out, as only they have to come to a referral center for multiple treatments.
To determine the AKI status of a patient, we used urine GFR criteria and urine output criteria or, if the two differs, we used the one that gives a more severe AKI classification.> -wrap-foot> The criteria that lead to the worst possible classification should be used.
There was no suggestion that breast cancer risks were increased with more intensive use of antidepressants or that antidepressant use is associated with a more severe stage of cancer at diagnosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com