Sentence examples for using a molecular simplification from inspiring English sources

Analogues of 8-chloro-N- 3-morpholinopropyl -5H-pyrimido[5,4-b]indol-4-amine 1, a known cruzain inhibitor, were synthesized using a molecular simplification strategy.

The synthetic analogues were designed from the lead compound, (1), using a molecular-simplification strategy.

Instead, they used a "molecular clock".

Models were compared using a model simplification approach based on the removal of the least significant terms, using Wald statistics, until only significant terms remained.

We used a backward model simplification procedure by first fitting saturated models.

The present model uses a simplification of the MMP dynamics, not taking into account protease synthesis, activation, inhibition, or internalization.

In reality this is not the case, and thus, we used a simplification.

One solution may be using a gel that hardens with a molecular structure similar to glass.

Thus, the goal of this study was to explore the antinociceptive potential, safety and mechanism of action of novel 1-pyrazole methyl ester derivatives, which were designed by molecular simplification, using in vivo and in vitro methods in mice.

Model simplification was performed using a backward stepwise algorithm.

This simplification is validated using a case study example.