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All fitting procedures were undertaken using a mean fit of R2 of 0.93 ± 0.13.
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Fitting was performed using a Gaussian fit and showed a mean force of 92.85 ± 33.72 pN.
Figure 3B represents the distribution of individual CD81 trajectories at the non-polarized HepG2 cell membrane (50 100 trajectories per cell) calculated using a linear fit to the mean squared displacement (MSD) versus time plots.
We controlled for the possible bias created by the mean-variance correlation by calculating the residual of variance in expression versus mean expression using a cubic spline fit (λ = 0.1).
The coefficient of variation of the interspike interval was calculated using a Gaussian fit over the histogram with Neuroexplorer and Igor Pro 6. Coefficient of variation as = (SD fit) / (mean fit) × 100.
Fitting errors for each point were calculated as mean errors in α using an X-fit routine [32].
Model fit was estimated using a χ goodness-of-fit statistic, root mean squared error of approximation (RMSEA), standardized root mean squared residuals (SRMRs), and the Tucker-Lewis Index (TLI).
using an Eppendorf-fitted Dounce homogenizer.
The resulting distribution was fitted using a robust Gaussian distribution fitting procedure with outlier removal (10% of the data), and the mean and standard deviation (SD) were determined.
IC50 values were calculated using a nonlinear dose response curve fit and expressed as mean ± SEM.
The mean monthly presence of bluefin tuna was then analyzed in relation to the mean values of SST and PP using a least- square-fit regression [43].
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