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We also ran trend analyses using a linear exposure term.
In trend analyses using a linear exposure term, HRs per increase of 100 nSv/hr in dose rate were between 1.2 and 1.4 for all diagnostic groups except lymphoma, where it was close to 1.
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He estimated the relation between lung cancer risk and domestic radon exposure using a linear model: where β is the slope parameter of the exposure response relation, and X is the mean radon concentration in the exposure time window (ETW), defined as 5 30 years before study enrollment.
The association of DRS with miR-144 or NRF2 levels was analyzed using a linear mixed effect model adjusted with exposure conditions as fixed effects and with participants as a random effect.
The less-than-proportional increase in nitrite and nitrate systemic exposure was explained by a concentration-dependent increase in clearance using a linear model.
Alternatively we can model the exposure-outcome association smoothly as a function of time, for example using a linear model, β(t) = β0 + β1 t.
Economic benefits realized by lead exposure reduction under a log-linear dose response function are more than twice that previously estimated using a linear dose response function.
Assuming a linear exposure response function leads to overestimation of the impact of peak exposures.
We modeled air pollution exposure using a continuous, linear form.
Using a continuous exposure will give more statistical power if a log-linear association exists between exposure and risk of a defect.
Similar to Type A questions, Type B questions (Table 2) can be addressed by establishing a P-value for the slope using a prespecified linear model of effects vs. exposure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com