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Using gene family assignments from the Ensembl project [26] (version 41 – October 2006; www.ensembl.org) we assign probabilities to the observed changes in gene family size along each mammalian lineage using a likelihood method that makes efficient use of genomic data in a phylogenetic context [25].
The cut-off 3.5 ng/mL was selected using a likelihood method as previously described [ 29].
Genotypes for each offspring and all possible sires were analyzed with the program Cervus [ 21], which assigns paternity using a likelihood method.
Therefore, I tested for evidence of recombination in centromeres using a likelihood method [ 21] and the classic four-gamete test for recombination [ 22].
Θ was estimated at 0.03009 using a likelihood method that relaxes the infinite sites assumption (LDhat) and at 0.04497 using the infinite sites Watterson estimate (DNAsp5).
The binary data are then converted to genetic distances using a likelihood method intended to compensate for the shortcomings of using a single reference taxon for CGH.
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In order to distinguish the background rate of change in chromosome number from doublings caused by WGDs, we used a likelihood method in which the background rate of chromosome number evolution is modeled as a birth death process.
Given a training data set of unphased genotypes and their corresponding phased HLA alleles, they used a likelihood method to compute probabilities associated with all possible pairs of HLA alleles and their particular haplotypes.
This method first estimates the generation time distribution using a likelihood based method.
Using a likelihood-based method and a nonparametric method, we estimate the serial interval and reproductive number throughout the course of each outbreak.
The test for positive selection was conducted using a likelihood-based method, where the likelihood of different evolutionary models is computed given a gene sequence alignment and a reconstruction of the phylogenetic history of the genes.
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