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The most reliable approach will be to reanalyze the data after more cases accumulate, both to assess whether the association with myeloma persists and to further evaluate confounding and selection bias using a larger case group to support analyses.
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To conclude; using a large case control material and simple, straightforward statistical analysis we have shown that HLA-A confers an additional influence on MS susceptibility in the Swedish population, not attributable to the known HLA-DRB1 association.
Moreover, by using a large case register linked to national mortality data, all those patients receiving secondary mental healthcare in our catchment area who died by suicide over 2007 2011 were included in the study with the only exception of those who ended their lives outside the UK.
Slattery and coworkers [ 8] used a large case-control study, including both white and Hispanic women, to examine the association between breast cancer and rs1805097 (G1057D), a SNP that had previously been associated with both colon cancer [ 11] and obesity [ 30].
We analyze and validate the proposed downsizing MIP model with a series of systematically generated test cases while its robust counterparts are studied extensively using a large generated case.
The new algorithm and the two FPGA architectures are evaluated using a large-scale case study from genetics.
In the future, we will need to optimize the parameters by using a larger number of cases.
However, as PCR experiments were performed using a larger number of cases than SAGE, we observed high variability of gene expression among the samples.
After years of playing with a quaint 90-square-inch head, he was finally joining the rest of the world in using a larger racket — in this case a 98-square-inch one.
The BP-ANN was trained by using a large (>1,000 cases) heterogeneous data set containing masses and microcalcifications.
Using a larger multicentre case control study of lung cancer in Europe, which included the above UK data (Simonato et al, 2001), we investigated whether the absolute risks of lung cancer in men are similar in other European countries with different smoking patterns and in different stages of the lung cancer epidemic.
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