Sentence examples for using a genetic variant from inspiring English sources

By using a genetic variant associated with smoking heaviness as a proxy for smoking heaviness, bias from confounding is minimised and findings are not affected by reverse causality.

By using a genetic variant associated with smoking heaviness as a proxy for smoking heaviness, bias from confounding is minimised and findings not affected by reverse causality.

Mendelian randomization using a genetic variant related to alcohol intake (ADH1B rs1229984) was used to obtain unbiased estimates of the association between alcohol intake and cognitive performance.

As an additional exploratory analysis, we performed a Mendelian randomization analysis, using a genetic variant associated with smoking behaviour as a proxy for smoking during pregnancy.

35 Thus, a simple interpretation of a mendelian randomisation analysis using a genetic variant in an alcohol metabolising enzyme is that it is akin to a long term randomised trial of more versus less alcohol exposure.

Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730) as a proxy for smoking heaviness, and observational meta-analyses of the associations of smoking status and smoking heaviness with depression, anxiety and psychological distress.

The NeuroIDgenetix® test uses a genetic variant panel of ten genes, along with concomitant medications, to make medication management recommendations based on gene-drug and drug-drug interactions for over 40 medications used in the treatment of depression and anxiety.

We have used a genetic variant that influences circulating folate levels to test whether low folate availability is a risk factor for obesity.

In the absence of a viable randomised trial to confirm or refute the cardioprotective effect of light to moderate alcohol consumption, an alternative approach is to use a genetic variant that serves as a proxy for alcohol consumption.

In their original report on the C2/CFB locus in ARM, Gold et al. [60] did not include LOC387715 variants and, using a genetic algorithm search approach, they arrived at a genetic risk model of two CFH variants and three C2/CFB variants.

For this purpose, a native soluble form of the HA50 274 protein was produced by expression in E. coli BL21 (DE3) pLysS variant C41, using a genetic construct that included a peptide signal for periplasmic expression.