Sentence examples for using a genetic screen from inspiring English sources
Using a genetic screen, we demonstrate that a region of extended homology N-terminal to the basic DNA binding domain is required for this dual site recognition.
By using a genetic screen to introduce random mutations into the animals' T cells, the researchers found that interfering with PD-1 expression reliably induced massive proliferation of cancerous T cells.
Here, using a genetic screen in Arabidopsis thaliana, we identified the highly conserved FANCM helicase, which is required for genome stability in humans and yeasts, as a major factor limiting meiotic CO formation.
Using a genetic screen, we demonstrate that the same transcription factors that regulate the spatial pattern of cdc25 string) transcription encode its temporal activation.
In the case of rice, one strategy has been to identify genes controlling such interesting root traits, which relies on the direct identification of genetic regions conferring tolerance to a given stress using a genetic screen, GWAS, or QTL analyses (e.g. PUP1; Gamuyao et al. [2012]).
In summary, using a genetic screen and physiologic studies, we provide evidence that FimL regulates CyaB activity and cAMP production at a post-translational step and that both proteins exhibit polar localization.
By using a genetic screening approach in adult zebrafish, they were able to pinpoint a single gene, SETDB1, that accelerates the onset of melanoma.
To investigate the effects of the same GCRs in both haploid and diploid contexts, studies were performed on mutant strains of S. cerevisiae selected using a genetic screening method based on a mutated allele of the URA2 gene [ 18].
We used a genetic screen to functionally identify Xcv TTSS effectors.
Here we have used a genetic screen in yeast to select in vivo peptides coupled to thioredoxin, called aptamers, that could inhibit GEFD2 activity.
In this study, we used a genetic screen to identify two mutations in the catalytic domain of yeast Sir2 that allow the enzyme to function in an NAD+-depleted environment.
