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The evaluation of which Gene Ontology (GO) classes are differentially methylated between tumor and surrounding samples was performed using a functional class scoring analysis as previously described [29].
The evaluation of which Gene Ontology (GO) classes are differentially expressed between control and affected bones was performed using a functional class scoring analysis as described previously [ 2].
The evaluation of pathways that are differentially expressed between ERαS305P positive and ERαS305P negative samples was done using a functional class scoring analysis as previously described [ 35].
The evaluation of which Gene Ontology (GO) classes are differentially expressed between pre- and post-treatment samples was performed using a functional class scoring analysis as described (Pavlidis et al, 2004).
The evaluation of the gene ontology (GO) classes that are differentially expressed between control and affected bones was performed using a functional class scoring analysis as described previously [ 26].
We calculate the p-value using a Functional Class Scoring (FCS -like procedure [ 21] where FCS -likereal cluster, we generate random clusters of size n 10,000 times, and calculate a randomised liprocedurent in a similar manner.
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Assignments of worm and fly genes to EggNOGs (Jensen et al. 2008) were used to ascribe a functional class (Tatusov et al. 2003) to a worm-fly pair of orthologs.
NGS-SNP [ 12] was used to assign a functional class to each SNP and to provide several fields of information describing the affected transcript and protein, if applicable (Additional file 4).
To address this issue, we have developed a new electrochemical sensor that uses a functional spiropyran, an important class of photo and thermochromic compounds, as both recognition receptor and latent redox mediator, to realize simultaneous photochemical and target-modulated electron transfer.
This is just a characteristic of a functional class: surely, we cannot use any weighted metric, where any potential approaches are lost.
Given the interdependence between WHO functional class and plasma BNP concentration, two models of bivariate analysis were analyzed: a model using WHO functional class and hyperbilirubinemia (both categorical data, Model 1) and a model using BNP and bilirubin concentration (both continuous data, Model 2).
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