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It is based on data from more than 30 000 patients enrolled in 16 randomised clinical trials, 15 of them using a double blind design and all including an independent and blinded assessment of outcomes.
Using a double blind RCT design, Swann et al. (1999) investigated the effect of episode number on response to treatment in 154 inpatients with bipolar disorder.
Using a double blind, parallel group study design, 15 patients with COPD, all habitual smokers, were randomised to receive nebulised sidenadet (3 mg tid; n= 7) or salbutamol (5 mg tid; n= 8) for 10 days.
The effect of high frequency (HF) rTMS on Stroop performance of 20 right-handed healthy female volunteers was tested using a double blind within subjects design by counterbalanced crossover sham (placebo) and active rTMS over the right DLPFC.
The effects of early postpartum maternal vitamin A supplementation (200,000 IU) on vitamin A status and growth of healthy breastfed infants were examined using a double blind controlled prospective study design.
The study was conducted in Djalakorodji, a peri-urban area of Bamako, Mali, using a double blind setup in which As+SMP was compared with praziquantel (PZQ).
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The study was conducted using a double-blind design.
Using a double-blind, controlled, randomized design, we evaluated its effects on endothelial function in women.
This finding was replicated in a second set of subjects using a double-blind task design.
Carnitine or a placebo (cellulose) was randomly assigned to the participants using a double-blind design.
Using a double-blind, counterbalanced design, 50 mg of naltrexone and placebo were administered.
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