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This includes the minimization of the Tikhonov functional which was done in [5] using a direct search method.
An introduction to effective discrete optimization algorithms, which can search for an optimum solution quickly using a direct search method, is followed.
To accomplish the task, the nonlinear subproblems at fixed structures have been decomposed into design and operating optimization levels, the former being facilitated by using a direct search method and the latter by using the reduced dimensional stochastic procedure.
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Nelder-Mead method uses a direct search algorithm without computing gradients.
When forced to prune the search space due to limitations on memory and time, it uses a directed search which favors good solutions over distinctly poorer ones.
Optimization was performed using a direct numerical search, gradient-based optimization, and genetic algorithm.
A search using the GenBank gene ID is also possible in 'Sequence ID Search.' For expert use, a direct search using the cluster ID is also available.
This paper considers the use of a direct search optimisation approach.
In addition, for groups 2 and 3, the cut-offs were optimised using a Monte Carlo direct search method [ 38] to find a set of antigen-specific cut-offs yielding the maximum sensitivity for the fixed specificity of 90%.
Finally, the TPWL model is used as a surrogate in a direct search optimization algorithm, and comparison with results using the full-order model demonstrates the efficacy of the enhanced TPWL procedures for this application.
A direct search method is used for minimum weight optimization.
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