Sentence examples for using a different sirna from inspiring English sources
Similar results were obtained by using a different siRNA against PHD1 (Fig 1D and E).
Similar results were obtained using a different siRNA to silence BAG3 excluding off-target effects (Supplementary Figure 1A).
We confirmed that FKBP51 knockdown resulted in ABCB5 decrease in several melanoma cell lines, using a different siRNA (Supplementary Figure S3).
As confirmation of these findings, transient knockdown of VDAC1 using a different siRNA sequence also prevented caspase-3 activation following TRAIL.
Importantly, these results were reproduced using a different siRNA targeting the 3′UTR of BUBR1 mRNA (Fig. 2C), excluding a possible off-target effect of siRNA.
A similar result was also observed using a different siRNA (siVRK2-M) (Supplementary Figure S2).The release of cytochrome c should activate caspases that could be detected by processing of PARP.
As shown in Supplementary Figure 8A, similar effects were produced when we used a different siRNA targeting GCN5.
Our previous studies investigating the function of RAIDD in NGF-deprivation-induced neuronal death used a different siRNA sequence and did not use Pen1 to deliver the siRNA [ 13].
Simpson et al. independently reported that KIF1C depletion resulted in inhibition of VSV-G transport using a different KIF1C siRNA.
Based on in vitro and in vivo evidence [16], [19], more pronounced α-synuclein suppression could conceivably be achieved by increasing the dosage of siRNA, testing other siRNA molecules or using a different method for siRNA delivery (e.g. viral vector).
Similar results were obtained using a different B7-H1-siRNA (CD274: siRNA ID = s26548) inhibitor (Additional file 1) confirming the specific inhibition effect of B7-H1.
