Sentence examples for using a diabody derived from inspiring English sources

Using a diabody derived from a monoclonal antibody (12G4) directed against the human anti-Müllerian hormone receptor, a biomarker of ovarian cancers for which therapeutic antibodies are already undergoing clinical trials, we describe here a new diabody refolding protocol with various reducing conditions.

As targeting moiety a diabody derived from the previously humanized scFv SGIII with grafted specificity of the murine anti-CD22 mAb RFB4 was constructed.

In conclusion, a diabody derived from the well-established anti-PSMA antibody J591 was engineered and shown to specifically target PSMA-positive tumours allowing for SPECT imaging with high contrast from 4 to 8 h post injection.

In this study a diabody derived from mAb J591 was developed as a single photon emission computed tomography (SPECT) tracer with improved pharmacokinetics for the detection of PSMA expression in prostate cancer.

Here we describe the development and preclinical evaluation of a diabody derived from the anti-PSMA antibody J591, site-specifically labelled with 99mTc, for SPECT imaging of PSMA expression in prostate cancer.

He simply never wanted to use an animal derived collagen.

Alternatively, Bioeffect uses an EGF derived from barley.

Targeting two tumour-associated antigens as a mechanism for modulating signalling within the tumour cell to elicit a therapeutic effect was validated by Zu and colleagues using a single-gene bs-diabody molecule specific for VEGFR2 (KDR) and VEGFR3 (Flt-4).

But even research using stem cells derived from surplus embryos faces a rather uncertain future.

University of Pennsylvania researchers conducted a large-scale study using data derived from a National Health and Nutrition Examination Survey.

Murine IL-10 was appended at the C-terminus of the F8 antibody in noncovalent homodimeric scFv (diabody) format [ 10], using a five-amino-acid linker between variable heavy chain (VH) and variable light chain VL), and a 15-amino-acid linker between the antibody and muIL10.