Sentence examples for using a cosmopolitan reference from inspiring English sources

The black curves represent our suggested strategy of using a cosmopolitan reference panel.

The high-level results of our cross-validation experiment are shown in Figure 2. As before, the solid black curves depict IMPUTE2 results with our suggested strategy of using a cosmopolitan reference panel, and different points on the x-axis correspond to different values of k hap.

To simplify the process of choosing reference haplotypes from a diverse collection, our approach uses a cosmopolitan reference panel.

A simple alternative is to use a "cosmopolitan" reference set that includes all available haplotypes, each of which is assigned an equal chance of being copied a priori.

Phenotypically plastic responses to acidified conditions are repeatedly evaluated using a cosmopolitan pelagic coccolithophorid species, Emiliania huxleyi (Lohmann).

A cosmopolitan reference panel produced high imputation accuracy in both frequency classes, but the accuracy at common SNPs came almost entirely from the most closely related panels.

For a focal African genome within a particular window, the method compares this genome against a cosmopolitan reference panel and assesses whether its genetic distance to this reference panel is on the level expected for a sub-Saharan genome or if instead this resembles a comparison of one cosmopolitan genome against others (indicating admixture).

We performed a series of experiments to evaluate our proposed imputation framework, which combines a cosmopolitan reference panel with a new approximation for speeding up imputation from large reference datasets.

On the basis of our findings, we propose an imputation framework with two basic components: (i) a cosmopolitan reference panel and (ii) a new algorithmic approximation that maintains the accuracy of large, diverse panels while controlling computational costs.

Additional copies of these alleles (and their associated haplotype backgrounds) may sometimes be found in other populations, which explain why a cosmopolitan reference panel can improve imputation accuracy at low-frequency variants.

These results support our strategy of using cosmopolitan reference panels: regardless of which reference data are available, the highest accuracy is achieved when using all available haplotypes and letting the imputation method decide which ones to use.