Sentence examples for using a conditional knockout from inspiring English sources

On-going studies using a conditional knockout mouse model for Dhs will help us to more clearly differentiate the impacts of DOHH and DHS function in higher eukaryotes.

Herein, we sought to specifically address the role of Cbfβ in cartilage and bone development by using a conditional knockout (CKO) approach.

Here, we examined T cell and thymic epithelial cell development using a conditional knockout approach.

The most appropriate approach to avoid this kind of bias would be using a conditional knockout model.

Using a conditional knockout (KO) mouse model for Cobra1, we demonstrate a critical role of Cobra1 in early embryonic development.

The requirement of NBS1 for efficient CSR has also been demonstrated by analyzing NBS1-deficient mouse B cells using a conditional knockout strategy [29], [30].

To test this hypothesis, we used a conditional knockout approach to eliminate E-cadherin specifically in the intestinal epithelium during embryonic development.

Therefore to analyze the Smad1 function in cartilage we used a conditional knockout strategy to specifically delete Smad1 in the growth plate by crossing mice with a floxed Smad1 allele to transgenic mice carrying Cre recombinase driven by the type II collagen promoter (Col2a1-cre) [25].

We therefore used a conditional knockout allele of Runx1 (Runx1 L/L ) (Li et al., 2006b).

In these experiments, we used a conditional knockout approach to understand how Cited2 deficiency results in cardiac phenotypic heterogeneity.

In this study, we use a conditional knockout strategy to establish a requirement for Cited2 in adult HSCs.