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Using a computational protocol designed to predict small-molecule binding to the cytoplasm-accessible spiroindolone pocket, we selected seven of the whole-cell inhibitors for further study.
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The only requirement for using a computational site is the existence of a standard user account and accessibility over the SSH protocol.
Pure geometry and abstraction take over, as he reframes his subjects using a computational method of triangulation.
Computational prediction of AS-NMD was performed using a computational pipeline based on that described previously [ 112, 113].
This study demonstrates the simplicity with which one can construct a set of nucleic acid computing units using a new computational protocol.
Colony sizes were measured in pixel units from digital images of double-mutant plates and normalized for experimental systematic effects with the use of a computational protocol developed for genetic interaction analysis (Baryshnikova et al. 2010b).
Using a simple computational protocol designed to approximately mimic a micropipette setting, we show that asymmetric incorporation of LPC can lead to significant curvature in a bilayer.
In Ramlan and Zauner [30], using a variant computational protocol (in this paper referred as P-ER1) developed from the original suggested by Penchovsky and Breaker [15], we have demonstrated the possibility of producing more diversified structural configurations for the molecular PASS gates, which are quite unique, compared to the homogeneous configurations implemented in the original protocol.
Here, we use a simple computational protocol to map the binding landscape for two homologous high-affinity complexes, involving a snake toxin fasciculin and acetylcholinesterase from two different species.
53 Based on these intergenic conservation profiles, a computational protocol was developed to compute sRNA elements in bacteria.
In this study, a computational protocol, slightly modified from Ludemann and coworkers' method [22], was used for REMD simulations.
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